Andras Perl Selected Research

Antinuclear Antibodies

10/2015	Liver injury correlates with biomarkers of autoimmunity and disease activity and represents an organ system involvement in patients with systemic lupus erythematosus.
10/2014	HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.
2/2010	Pathogenic mechanisms in systemic lupus erythematosus.
2/2010	Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.
9/2009	Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome.
9/2009	T-cell and B-cell signaling biomarkers and treatment targets in lupus.
7/2007	Immunofluorescence microscopy is superior to fluorescent beads for detection of antinuclear antibody reactivity in systemic lupus erythematosus patients.
12/2006	Signaling abnormalities in systemic lupus erythematosus as potential drug targets.
2/2006	The role of nitric oxide in abnormal T cell signal transduction in systemic lupus erythematosus.
1/2005	T- and B-cell abnormalities in systemic lupus erythematosus.

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Andras Perl Research Topics

Disease

42	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 01/2002
16	Inflammation (Inflammations) 01/2022 - 01/2002
12	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 02/2006
10	Necrosis 09/2013 - 01/2002
7	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2005
6	Infections 01/2022 - 11/2006
6	Proteinuria 01/2022 - 01/2013
5	Multiple Sclerosis 04/2010 - 01/2004
4	Lupus Nephritis 01/2022 - 01/2013
4	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2020 - 06/2015
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 06/2009
3	Fibrosis (Cirrhosis) 01/2022 - 03/2016
3	Thrombocytopenia (Thrombopenia) 07/2020 - 10/2015
3	Liver Diseases (Liver Disease) 01/2020 - 10/2015
3	Rheumatoid Arthritis 01/2020 - 12/2017
3	Arthritis (Polyarthritis) 01/2020 - 02/2004
3	Neoplasms (Cancer) 06/2015 - 11/2009
2	Myotoxicity 01/2020 - 01/2008
2	Liver Failure 01/2020 - 06/2009
2	Exanthema (Rash) 01/2018 - 02/2004
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 11/2015 - 05/2013
2	Male Infertility (Male Sterility) 07/2011 - 06/2007
2	Liver Cirrhosis (Hepatic Cirrhosis) 06/2009 - 09/2004
1	Castleman Disease (Castleman's Disease) 12/2021
1	Headache (Headaches) 01/2021
1	Hematuria 01/2021
1	Reinfection 01/2021
1	COVID-19 10/2020
1	Coronavirus Infections 10/2020
1	Hemolysis 10/2020
1	Glucosephosphate Dehydrogenase Deficiency 10/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 09/2020
1	Fever (Fevers) 07/2020
1	Adult-Onset Still's Disease 07/2020
1	Anemia 07/2020
1	Hyperferritinemia 07/2020
1	Splenomegaly 07/2020
1	Macrophage Activation Syndrome 07/2020
1	Atrophy 01/2020
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2020
1	Discitis 01/2020
1	Muscular Diseases (Myopathy) 01/2020
1	Thrombotic Microangiopathies 01/2020

Drug/Important Bio-Agent (IBA)

18	Sirolimus (Rapamycin)FDA Link 01/2022 - 09/2006
11	Adenosine Triphosphate (ATP)IBA 01/2012 - 01/2002
10	Antinuclear AntibodiesIBA 10/2015 - 01/2005
8	Acetylcysteine (Siran)FDA LinkGeneric 10/2020 - 06/2009
7	AntioxidantsIBA 01/2022 - 06/2009
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2006
7	Glutathione (Reduced Glutathione)IBA 10/2020 - 05/2004
7	TransaldolaseIBA 01/2020 - 01/2004
6	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 10/2006
6	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2020 - 07/2002
5	Mechanistic Target of Rapamycin Complex 1IBA 01/2022 - 05/2014
5	EnzymesIBA 10/2020 - 06/2009
4	Glucose (Dextrose)FDA LinkGeneric 10/2020 - 06/2007
4	AntibodiesIBA 01/2020 - 01/2004
3	Oxidoreductases (Dehydrogenase)IBA 10/2020 - 06/2007
3	Antigen-Antibody Complex (Immune Complex)IBA 01/2020 - 02/2010
3	TOR Serine-Threonine KinasesIBA 01/2018 - 09/2009
3	AutoantibodiesIBA 11/2013 - 08/2005
3	Oxygen (Dioxygen)IBA 01/2013 - 07/2002
2	Mechanistic Target of Rapamycin Complex 2IBA 01/2022 - 03/2016
2	SteroidsIBA 01/2021 - 01/2020
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 10/2020 - 01/2020
2	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2020 - 01/2020
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 07/2020 - 01/2020
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020 - 06/2015
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 06/2009
2	MTOR InhibitorsIBA 01/2020 - 06/2015
2	Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA 01/2020 - 04/2010
2	Pharmaceutical PreparationsIBA 01/2020 - 12/2006
2	TransketolaseIBA 01/2020 - 06/2007
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2016
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2014 - 11/2012
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2013 - 02/2006
2	CytokinesIBA 12/2011 - 06/2009
2	Nuclear Proteins (Protein, Nuclear)IBA 02/2010 - 08/2005
2	Interferon-alpha (Interferon Alfa)IBA 06/2009 - 01/2005
2	CalciumIBA 02/2009 - 09/2006
1	IntegrinsIBA 01/2022
1	Adenosine (Adenocard)FDA LinkGeneric 01/2022
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2022
1	Complement C3 (C3 Complement)IBA 01/2022
1	Serum AlbuminIBA 01/2022
1	InterferonsIBA 01/2021
1	Complement C4 (Complement Component 4)IBA 01/2021
1	Interleukin-2 (IL2)IBA 01/2021
1	Ferritins (Ferritin)IBA 10/2020
1	C-Reactive ProteinIBA 10/2020
1	EmapalumabIBA 07/2020
1	Histocompatibility Antigens Class IIBA 01/2020
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2020
1	mitoquinoneIBA 01/2020
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2020

Therapy/Procedure

4	Therapeutics 01/2021 - 07/2014
1	Membrane Oxygenators (Membrane Oxygenator) 10/2020
1	Mechanical Ventilators (Ventilator) 10/2020
1	Secondary Prevention 09/2020
1	Artificial Respiration (Mechanical Ventilation) 01/2020